Bioinformatics Analysis Reveals Distinct Oncogenic Profiles of HPV-16 and HPT-18 to Other Subtypes in Cervical Cancer | Synapse
April 10, 2026Open Access
Bioinformatics Analysis Reveals Distinct Oncogenic Profiles of HPV-16 and HPT-18 to Other Subtypes in Cervical Cancer
Key Points
The analysis aims to identify specific genetic profiles associated with HPV-16 and HPV-18 in cervical cancer.
Conducted bioinformatics analysis of gene expression data
Focused on HPV-16 and HPV-18 subtypes
Identified key genes associated with disease progression
Identified BUB1, DLGAP5, and ASPM as genes expressed in HPV-16/18-related cervical cancer
Suggests these genes as potential biomarkers for prognosis
Highlights distinct oncogenic profiles compared to other subtypes
Abstract
This analysis identified BUB1, DLGAP5, and ASPM as key genes specifically expressed in HPV-16/18-related cervical cancer, suggesting their potential as biomarkers for prognosis and disease progression.