TRIM32 variants associated with limb girdle muscular dystrophy type R8 are distributed across most protein domains and do not predict clinical severity.
TRIM32 variants in LGMDR8 do not predict clinical severity, and the disease has a highly variable age of onset.
Absolute Event Rate: 0% vs 0%
LGMDR8 is very rare in non-Hutterite patients. Age of onset is highly variable. Variants are distributed across most protein domains and did not predict clinical severity.
Guérémy et al. (Mon,) reported a other. TRIM32 variants associated with limb girdle muscular dystrophy type R8 are distributed across most protein domains and do not predict clinical severity.