Comparison of eight insulin resistance surrogate indices in predicting incident stroke among middle-aged and older individuals without diabetes: a nationwide prospective cohort study

Key Points

• This study aims to compare various insulin resistance surrogate indices to determine their effectiveness in predicting stroke risk among older adults without diabetes.
• Nationwide prospective cohort study design
• Involved middle-aged and older individuals without diabetes
• Compared eight different insulin resistance surrogate indices
• Analyzed correlation of indices with incident stroke occurrences
• eGDR showed superior predictive capability for stroke risk compared to other indices
• Indicated potential for eGDR as an early assessment tool for stroke risk
• Findings highlight the importance of effective risk assessment strategies in aging populations