Mechanosynthesis of cocrystals and coamorphous binary drug–drug systems with apremilast core: structural and biological studies | Synapse
April 10, 2026Open Access
Mechanosynthesis of cocrystals and coamorphous binary drug–drug systems with apremilast core: structural and biological studies
Key Points
This research aims to understand how pharmaceutical binary systems form and ensure their safety in therapies.
Analyzed mechanosynthesis techniques for cocrystals and coamorphous systems.
Examined structural properties of drug-drug combinations.
Conducted biological studies on the safety and efficacy of the systems.
Identified successful formation techniques for stable binary systems.
Observed enhanced drug interactions that may improve therapeutic outcomes.
Found that certain combinations showed promising safety profiles.
Abstract
In this paper, we discuss an issue important for understanding the mechanism of forming pharmaceutical binary systems and their safety in specific therapies. The main aim of this article is...