Despite high awareness of recommendations for GnRH agonists, the clinical implementation of GnRH analogs for ovarian protection remains limited in Japan. Institutional characteristics and policy-related factors were associated with reported GnRH agonist use, although causal relationships cannot be inferred. These findings highlight a gap between current clinical practice and available evidence and underscore the need for careful evaluation of the role of GnRH analogs within existing fertility preservation frameworks.
Sakaguchi et al. (Wed,) studied this question.