September 15, 2011Open Access

Factors Associated With Virological Failure in HIV-1–Infected Patients Receiving Darunavir/Ritonavir Monotherapy

Key Points

Key points are not available for this paper at this time.

Abstract

Factors associated with virological failure in patients receiving DRV/r monotherapy were having an initial blip, shorter time of antiretroviral treatment before monotherapy, and an adherence <100% during monotherapy. The importance of prior duration exposure to ART was in agreement with the impact of HIV-1 blood reservoir and VL level at baseline.

Read Full Paperexternally

问 AI

Bookmark

View Full Paper

Cite This Study

Lambert-Niclot et al. (Thu,) studied this question.

synapsesocial.com/papers/69d975e05e5bcb4e3b8368f0 https://doi.org/https://doi.org/10.1093/infdis/jir518

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Impact of 48 week lopinavir/ritonavir monotherapy on blood cell-associated HIV-1-DNA in the MONARK trial2010 · 23 citations
2Initial therapy with nucleoside reverse transcriptase inhibitor-containing regimens is more effective than with regimens that spare them with no difference in short-term fat distribution: Hippocampe-ANRS 121 Trial2008 · 18 citations
3Lopinavir/ritonavir monotherapy or plus zidovudine and lamivudine in antiretroviral-naive HIV-infected patients2008 · 137 citations
4New Real-Time Reverse Transcriptase-Initiated PCR Assay with Single-Copy Sensitivity for Human Immunodeficiency Virus Type 1 RNA in Plasma2003 · 611 citations
5LTR real‐time PCR for HIV‐1 DNA quantitation in blood cells for early diagnosis in infants born to seropositive mothers treated in HAART area (ANRS CO 01)2008 · 196 citations

问 AI

Bookmark

View Full Paper