A novel quantification technique revealed significant differences in vascular calcification and cardiovascular dysfunction across advanced CKD and dialysis patients, highlighting that a substantial minority remain free of calcification.
This study has successfully utilized a novel technique for the quantification of calcification. We have demonstrated vascular calcification and associated cardiovascular dysfunction in CKD 4, PD and HD with significant differences between the groups. Thirty percent of individuals show no calcification, even those established on renal replacement therapy for a prolonged period of time. Further work is required to identify factors which promote progression of arterial calcification in those who are susceptible.
Sigrist et al. (Tue,) studied this question.