Are midlife cardiovascular risk factors (hypertension, diabetes mellitus, and smoking) associated with accelerated cognitive decline in midlife?
Midlife cardiovascular risk factors (hypertension, diabetes, smoking) are associated with accelerated cognitive decline, identifying them as potential modifiable targets to prevent cognitive aging.
Midlife CVRFs, especially hypertension, diabetes mellitus, and smoking, are common and associated with accelerated cognitive decline at midlife. These results identify potential modifiable targets to prevent midlife cognitive decline and highlight the need for a life course approach to cognitive function and aging.
Yaffe et al. (2020) studied this question.