July 16, 2020Neurology103 citationsOpen Access
View Full PaperCardiovascular risk factors and accelerated cognitive decline in midlife
Structured PICO
Are midlife cardiovascular risk factors (hypertension, diabetes mellitus, and smoking) associated with accelerated cognitive decline in midlife?
P
Population
Individuals in midlife
I
Intervention
Presence of midlife cardiovascular risk factors (specifically hypertension, diabetes mellitus, and smoking)
O
Outcome
Accelerated cognitive decline at midlife
Midlife cardiovascular risk factors (hypertension, diabetes, smoking) are associated with accelerated cognitive decline, identifying them as potential modifiable targets to prevent cognitive aging.
Abstract
Midlife CVRFs, especially hypertension, diabetes mellitus, and smoking, are common and associated with accelerated cognitive decline at midlife. These results identify potential modifiable targets to prevent midlife cognitive decline and highlight the need for a life course approach to cognitive function and aging.