Does aptamer-based proteomic profiling reveal novel candidate biomarkers and pathways in cardiovascular disease?
Aptamer-based proteomic profiling offers a high-sensitivity and high-precision approach to discovering novel cardiovascular biomarkers.
Our results highlight an emerging proteomics tool capable of profiling >1000 low-abundance analytes with high sensitivity and high precision, applicable both to well-phenotyped perturbational studies and large human cohorts, as well.
Ngo et al. (2016) studied this question.