Does dietary chlorogenic acid attenuate hypertension and improve endothelial function in spontaneously hypertensive rats?
Dietary chlorogenic acid demonstrates potential to improve vascular health and lower blood pressure in a hypertensive rat model by reducing oxidative stress.
Dietary CQA reduces oxidative stress and improves nitric oxide bioavailability by inhibiting excessive production of reactive oxygen species in the vasculature, and leads to the attenuation of endothelial dysfunction, vascular hypertrophy, and hypertension in spontaneously hypertensive rats.
Suzuki et al. (2006) studied this question.