Elevated serum Slit3 independently predicts disease activity and interstitial lung disease in rheumatoid arthritis

Key Points

• The study investigates the relationship between serum Slit3 levels and disease activity in rheumatoid arthritis (RA) patients, specifically focusing on interstitial lung disease (ILD).
• Measured serum Slit3 levels in RA patients
• Assessed disease activity using clinical criteria
• Analyzed the correlation between Slit3 levels and RA-ILD incidence
• Higher serum Slit3 levels correlated with increased disease activity
• Elevated Slit3 was identified as an independent risk factor for RA-ILD
• Suggests potential for Slit3 as a biomarker for monitoring RA-ILD