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April 12, 2026Journal of Applied Clinical Medical Physics0 citationsOpen Access

Using deformable registration to assess dosimetric impact of variability in deep inspiration breath hold (DIBH) levels for left breast treatment

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VRVenketesh Thrithamara RanganathanAGAmy GouthroTSTynan Stevens

Key Points

  • This research aims to evaluate how variations in deep inspiration breath hold (DIBH) levels affect dosimetric outcomes in breast cancer treatment.
  • Utilized deformable registration for dose estimation
  • Compared the sensitivity of 3DCRT and VMAT to DIBH variability
  • Analyzed individual patient breath hold movements
  • 3DCRT showed less sensitivity to breath hold variability compared to VMAT
  • Significant individual variability in plan robustness was observed
  • The protocol supports personalized technique selection based on DIBH movements

Abstract

Deformable registration-based dose estimation reveals complex organ motion with significant individual variability in plan robustness. 3DCRT is less sensitive to BH variability than VMAT. Our protocol potentially enables individualized approach to selecting technique and tolerances based on patients' DIBH movements.

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Cite This Study

Ranganathan et al. (2026) studied this question.

synapsesocial.com/papers/69db37044fe01fead37c507bhttps://doi.org/10.1002/acm2.70541
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