Using deformable registration to assess dosimetric impact of variability in deep inspiration breath hold (DIBH) levels for left breast treatment

Key Points

• This research aims to evaluate how variations in deep inspiration breath hold (DIBH) levels affect dosimetric outcomes in breast cancer treatment.
• Utilized deformable registration for dose estimation
• Compared the sensitivity of 3DCRT and VMAT to DIBH variability
• Analyzed individual patient breath hold movements
• 3DCRT showed less sensitivity to breath hold variability compared to VMAT
• Significant individual variability in plan robustness was observed
• The protocol supports personalized technique selection based on DIBH movements