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January 7, 2009New England Journal of Medicine1,454 citationsOpen Access

Deletion of IKZF1 and Prognosis in Acute Lymphoblastic Leukemia

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CMCharles G. MullighanXSXiaoping SuJZJinghui Zhang

Key Points

  • This research aims to explore the impact of IKZF1 deletion on prognosis in acute lymphoblastic leukemia (ALL).
  • Analyzed genetic alterations in patients with B-cell-progenitor ALL.
  • Evaluated prognosis associated with IKZF1 deletion.
  • IKZF1 deletion is linked to significantly poorer outcomes in B-cell-progenitor ALL patients.

Abstract

Genetic alteration of IKZF1 is associated with a very poor outcome in B-cell-progenitor ALL.

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Cite This Study

Mullighan et al. (2009) studied this question.

synapsesocial.com/papers/69dbc6fc37b5141e3ba3d3f5https://doi.org/10.1056/nejmoa0808253
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