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September 19, 2012JAMA657 citations

Dysfunctional Adiposity and the Risk of Prediabetes and Type 2 Diabetes in Obese Adults

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INIan J. NeelandATAslan T. TurerCAColby Ayers

Structured PICO

Are excess visceral fat and insulin resistance associated with an increased risk of incident prediabetes and type 2 diabetes in obese adults?

P
Population
Obese adults
I
Intervention
Excess visceral fat and insulin resistance
O
Outcome
Incident prediabetes and type 2 diabetes mellitus

Visceral fat and insulin resistance, rather than general adiposity, are the primary drivers of incident prediabetes and type 2 diabetes in obese adults.

Abstract

Excess visceral fat and insulin resistance, but not general adiposity, were independently associated with incident prediabetes and type 2 diabetes mellitus in obese adults.

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Neeland et al. (2012) studied this question.

synapsesocial.com/papers/69dc5f2b4f901957bec104cehttps://doi.org/10.1001/2012.jama.11132
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