September 19, 2012JAMA
Dysfunctional Adiposity and the Risk of Prediabetes and Type 2 Diabetes in Obese Adults
Why the study?
Are excess visceral fat and insulin resistance associated with an increased risk of incident prediabetes and type 2 diabetes in obese adults?
Population
Obese adults
Design
Cohort
Authors
Discussion
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Member takes
Implication
May refine diabetes risk stratification beyond BMI in obese adults; hypothesis-generating and requires prospective confirmation.
Structured PICO
Are excess visceral fat and insulin resistance associated with an increased risk of incident prediabetes and type 2 diabetes in obese adults?
P
Population
Obese adults
I
Intervention
Excess visceral fat and insulin resistance
O
Outcome
Incident prediabetes and type 2 diabetes mellitus
Visceral fat and insulin resistance, rather than general adiposity, are the primary drivers of incident prediabetes and type 2 diabetes in obese adults.
Cite This Study
Neeland et al. (2012) studied this question.