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biopsy in our patients did not show evidence of Crohn's disease, but there was unequivocal evidence of Crohn's disease elsewhere. Furthermore, the failure of symptoms in patients who do not smoke to respond to treatment suggests peptic ulceration associated with Crohn's disease. Treatment with omeprazole led to prompt relief of symptoms and complete healing of ulceration, which was confirmed by endoscopy.
O’Donnell et al. (Sat,) studied this question.