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February 4, 2016Circulation Research1,425 citations

Revisiting Cardiac Cellular Composition

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APAlexander R. PintoAIAlexei IlinykhMIMalina J. Ivey

Structured PICO

P
Population
Cardiac cells/heart tissue
O
Outcome
Abundance of different cell types in the heart

Endothelial cells, rather than fibroblasts, constitute the majority of noncardiomyocytes in the heart, suggesting a greater role in physiological function and injury response than previously appreciated.

Abstract

This new perspective on the abundance of different cell types in the heart demonstrates that fibroblasts comprise a relatively minor population. By contrast, endothelial cells constitute the majority of noncardiomyocytes and are likely to play a greater role in physiological function and response to injury than previously appreciated.

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Cite This Study

Pinto et al. (2016) studied this question.

synapsesocial.com/papers/69dcd6f798c6111533e54513https://doi.org/10.1161/circresaha.115.307778
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