February 4, 2016Circulation Research
Revisiting Cardiac Cellular Composition
Population
Cardiac cells/heart tissue
Design
Review
Authors
Discussion
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Member takes
Implication
May redirect cardiac research priorities toward endothelial cells; hypothesis-generating for their role in injury response.
Structured PICO
P
Population
Cardiac cells/heart tissue
O
Outcome
Abundance of different cell types in the heart
Endothelial cells, rather than fibroblasts, constitute the majority of noncardiomyocytes in the heart, suggesting a greater role in physiological function and injury response than previously appreciated.
Cite This Study
Pinto et al. (2016) studied this question.