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Introduction: Elevated serum ferritin levels may be associated with chronic periodontitis (CP), and change in serum ferritin levels may be reflected in response to periodontal therapy. The aim of the present study is to identify the causal relationship if any between CP and serum ferritin levels.Materials and Methods: A total of 30 patients in the age group of 25–60 years were recruited from the Outpatient Department of Periodontics, Sri Siddhartha Dental College and Hospital Agalakote, Tumkur. Along with all the clinical parameters, each patient's blood was collected for in vitro assessment of serum ferritin levels at baseline and 1 month after nonsurgical periodontal therapy.Results: The mean reduction in serum ferritin levels from baseline and 1 month after nonsurgical periodontal treatment in CP patients was statistically highly significant. On comparison between normal healthy individuals, the mean difference in serum ferritin levels in CP patients was statistically highly significant.Conclusion: With the result obtained, serum ferritin levels can be used as a biomarker in evaluating the effectiveness of periodontal therapy. More interventional studies with larger sample size and long-term studies are needed to evaluate serum ferritin levels can be used as a biomarker for CP patients.
Nikesh Thounaojam (Tue,) studied this question.