Does preprocedural serum CRP predict the risk of myocardial infarction and angina in patients with severe peripheral vascular disease requiring revascularization?
Preprocedural serum CRP is a strong, independent predictor of MI in patients undergoing revascularization for severe PVD, suggesting a potential role for anti-inflammatory therapies.
The high incidence of MI in patients with PVD severe enough to require revascularization is strongly predicted by preprocedural measurements of serum CRP, independent of previous CAD, Eagle score index, and traditional cardiovascular risk factors. These patients may benefit from therapy modulating the inflammatory response.
Rossi et al. (Tue,) studied this question.