October 14, 2022Current Opinion in Lipidology62 citationsOpen Access
Consensus and guidelines on lipoprotein(a) – seeing the forest through the trees
Structured PICO
Should Lp(a) be measured to assess ASCVD risk?
P
Population
General population for ASCVD risk assessment
I
Intervention
Measurement of Lipoprotein(a) [Lp(a)] at least once in a lifetime
Emphasizes the consensus recommendation to measure Lp(a) at least once in a lifetime to identify and manage excess ASCVD risk.
Abstract
Since the contribution of high Lp(a) concentrations to global ASCVD risk has been underestimated in the past, a clear recommendation to measure Lp(a) at least once in a person's lifetime is imperative. Recent expert consensus recommendations provide clinicians with direction on how to manage the excess risk associated with elevated Lp(a) concentration by comprehensive and individualized management of modifiable ASCVD risk factors while awaiting the results of clinical trials of Lp(a) targeted therapies.