Salvianolic acid B inhibits proliferation, migration and aerobic glycolysis of melanoma cells via regulation of PKM2 in vitro

Key Points

• This research investigates how salvianolic acid B affects melanoma cell functions like proliferation and glycolysis.
• Evaluated the effect of salvianolic acid B on melanoma cell viability.
• Investigated the impact on abnormal glycolysis.
• Assessed the modulation of PKM2 expression.
• Salvianolic acid B significantly suppressed melanoma cell viability.
• The compound reduced aerobic glycolysis in melanoma cells.
• PKM2 expression was altered, linking it to the observed effects.