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December 9, 2011Stroke189 citationsOpen Access

Towards a Consensus-Based Classification of Childhood Arterial Ischemic Stroke

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TBTimothy J. BernardMMMarilyn J. Manco‐JohnsonWLWarren Lo

Key Points

  • Develop and assess the inter-rater reliability of the CASCADE criteria, a new consensus-based classification system for childhood arterial ischemic stroke.
  • Assessed a novel consensus-based classification framework (CASCADE criteria) for categorizing subtypes of childhood-onset arterial ischemic stroke.
  • Evaluated investigator agreement and inter-rater reliability to assess standardized implementation across multicenter study settings.
  • The CASCADE classification criteria achieved good inter-rater reliability among investigators evaluating childhood arterial ischemic stroke cases.
  • Preliminary findings indicate the criteria are particularly feasible and effective for standardized use in prospective multicenter pediatric research.

Abstract

A new, consensus-based classification system for childhood AIS, the CASCADE criteria, can be used to classify cases with good IRR. These preliminary findings suggest that the CASCADE criteria may be particularity useful in the setting of prospective multicenter studies in childhood-onset AIS, where standardized training of investigators is feasible.

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Cite This Study

Bernard et al. (2011) studied this question.

synapsesocial.com/papers/69deab4bafb501b9b65585fehttps://doi.org/10.1161/strokeaha.111.624585
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