Validation study demonstrates good inter-rater reliability for CASCADE criteria in childhood arterial ischemic stroke, suggesting utility in prospective multicenter clinical research.
A new, consensus-based classification system for childhood AIS, the CASCADE criteria, can be used to classify cases with good IRR. These preliminary findings suggest that the CASCADE criteria may be particularity useful in the setting of prospective multicenter studies in childhood-onset AIS, where standardized training of investigators is feasible.
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Bernard et al. (2011) studied this question.
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