Waning of measles immunity by 5 years of age following an accelerated two-dose measles vaccine schedule at 6 and 12 months in South African children: an observational cohort study

Key Points

• To investigate the duration of measles immunity in South African children after receiving two doses of vaccine.
• Conducted an observational cohort study
• Assessed measles immunity in children at age five
• Analyzed outcomes following an accelerated two-dose vaccine schedule
• Significant waning of measles immunity observed by 5 years of age
• Decreased antibody levels noted following the two-dose vaccine schedule
• Findings suggest a potential need for booster vaccinations