Short- versus long-course antibiotic therapy in mechanically ventilated sepsis patients with pneumonia: a real-world cohort analysis

Key Points

• This research aims to evaluate the relationship between the length of antibiotic therapy and 90-day mortality in mechanically ventilated sepsis patients with pneumonia.
• Conducted an observational cohort analysis
• Compared short-course and long-course antibiotic therapies
• Adjusted for potential confounding factors
• Shorter antibiotic courses did not lead to increased 90-day mortality
• Findings suggest potential signals that require further investigation
• Data indicates the need for randomized trials for confirmation