Hormonal replacement therapy in postmenopausal women ≥50 years is associated with the incidence of glaucoma: Evidence from 6576 females in Finland

Key Points

• To explore the relationship between hormonal replacement therapy (HRT) and the incidence of glaucoma in postmenopausal women.
• Analyzed data from 6576 postmenopausal women aged 50 years and older in Finland.
• Investigated the effects of different types of HRT on glaucoma risk.
• Focused on the subgroup with primary open-angle glaucoma (POAG).
• General use of HRT may increase the risk of glaucoma in postmenopausal women.
• Estrogen-only therapy showed a significant risk association specifically in the POAG subgroup.