Doxorubicin-loaded polyvinyl alcohol-chitosan-based nanofibers for antimicrobial therapy and real-time in-vivo imaging

Key Points

• This research aims to evaluate the effectiveness of doxorubicin-loaded nanofibers in antimicrobial therapy and wound healing.
• Synthesis of polyvinyl alcohol-chitosan-based nanofibers loaded with doxorubicin
• Testing antibacterial activity and wound-healing efficacy
• Assessment of physicochemical properties and biosafety
• Nanofibers showed strong antibacterial activity against pathogens
• Significant enhancement in wound healing observed in models
• Favorable biosafety profile indicates potential for clinical use.