What question did this study set out to answer?

This research aims to evaluate the role of CD62L low inflammatory eosinophils in thunderstorm-related asthma exacerbations in children.

April 15, 2026

Expanded peripheral CD62L low inflammatory eosinophils in pediatric thunderstorm‐related asthma exacerbations: A single‐center analysis

Key Points

This research aims to evaluate the role of CD62L low inflammatory eosinophils in thunderstorm-related asthma exacerbations in children.
Single-center analysis of circulating eosinophils in children during thunderstorms
Assessment of CD62L expression levels on inflammatory eosinophils
Evaluated cytokine responsiveness and activation status
Increased levels of CD62L low eosinophils observed in asthma exacerbations during thunderstorms
These eosinophils displayed heightened activation and cytokine responsiveness
Findings suggest a primed type-2 inflammatory profile in affected children

Abstract

Thunderstorm-related asthma is associated with a marked expansion of circulating CD62Llow iEOS that display heightened activation and cytokine responsiveness, indicating a primed type-2 inflammatory phenotype in susceptible children. Assessment of CD62Llow iEOS may be beneficial for early identification of children at high risk of thunderstorm-triggered exacerbations and help inform proactive preventive strategies.

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Cite This Study

Miao et al. (Wed,) studied this question.

synapsesocial.com/papers/69df2cf7e4eeef8a2a6b20de https://doi.org/https://doi.org/10.1111/pai.70349

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