Does inhibition of miR-320a prevent doxorubicin-induced cardiotoxicity?
Inhibition of miR-320a may serve as a potential therapeutic strategy for treating anthracycline-induced cardiac dysfunction.
Our observations demonstrate that miR-320a play important roles in doxorubicin induced cardiotoxicity via vessel homeostasis in heart and thus, inhibition of miR-320a may be applied to the treatment of cardiac dysfunction induced by anthracycline.
Yin et al. (Sat,) studied this question.