The U-shaped correlation between the systemic immune-inflammation index and all-cause and cardiovascular mortality in hyperlipidemic patients: findings from NHANES 1999–2018

Key Points

• This research aims to explore the relationship between the systemic immune-inflammation index and mortality rates in hyperlipidemic patients.
• Analyzed data from NHANES (1999-2018) for hyperlipidemic individuals.
• Investigated the correlation between systemic immune-inflammation index (SII) and all-cause as well as cardiovascular mortality.
• Assessed the non-linear relationship using statistical modeling.
• Found a U-shaped correlation between SII and all-cause mortality.
• Identified a similar U-shaped trend for cardiovascular mortality in hyperlipidemic patients.