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April 16, 2026HLA1 citations

Identification of the Novel HLA‐B*40:594N Allele by Next‐Generation Sequencing

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JYJianing YuanBXBin XiZSZheng Shi

Key Points

  • To identify and characterize the novel HLA-B*40:594N allele through sequencing techniques.
  • Utilized next-generation sequencing to analyze genetic material.
  • Focused on the HLA-B region for allele identification.
  • Compared the allele with HLA-B*40:02:01:01 to detect differences.
  • Identified a single nucleotide substitution in codon 164.
  • Characterized the novel HLA-B*40:594N allele as distinct from HLA-B*40:02:01:01.

Abstract

ABSTRACT The HLA‐B*40:594N allele differs from HLA‐B*40:02:01:01 by one nucleotide substitution in codon 164 in exon 3.

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Cite This Study

Yuan et al. (2026) studied this question.

synapsesocial.com/papers/69e07e3b2f7e8953b7cbf444https://doi.org/10.1111/tan.70718
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