Aims and Backgrounds: To review the current state of ultrasound energy-based devices and their role in facial and neck rejuvenation Historical Aspects: High-frequency ultrasound (HIFU) paved the way for the microfocused and parallel beam ultrasound technology in aesthetics. Anatomy: Facial and cervical aging reflects multilayered structural changes, as well as reduced collagen production and increased collagen breakdown at the histologic level resulting in rhytids and skin laxity. Technology: Microfocused ultrasound with visualization (MFU-V) is adapted from HIFU, using significantly less ultrasound energy and visualization to precisely target the deep dermis and superficial musculoaponeurotic system (SMAS) at depths ranging from 1.5 to 4.5 mm; Synchronous Ultrasound Parallel Beam (SUPERB) technology uses parallel transducers to deliver energy at a precise depth of 1.5 mm to target the mid-dermis. Patient Selection: Ultrasonic facial rejuvenation is ideal for those with mild to moderate skin laxity who desire incremental tightening and textural improvement without surgery. Techniques: MFU-V can be performed at different tissue depths based on transducer tip with various combination protocols described; SUPERB technology delivers energy at a fixed depth Postoperative Care: Self-limited erythema and edema, sun protection Current and Future Development: The intersection of ultrasonic devices and regenerative medicine is promising. Conclusions and Clinical Relevance: MFU-V and SUPERB are ideal noninvasive options for patients with mild to moderate skin laxity. Keywords: microfocused ultrasound with visualization, high‐intensity parallel beam ultrasound, noninvasive skin tightening, facial rejuvenation, ultrasound
Liao et al. (2026) studied this question.