The beneficial effects of leave extract of Commiphora leptophloeos on intestinal mucositis induced by 5-fluorouracil in mice

Key Points

• This research aims to evaluate the protective effects of Commiphora leptophloeos extract on intestinal mucositis caused by 5-fluorouracil in mice.
• Oral administration of a hydroethanolic extract of Commiphora leptophloeos to Swiss mice
• Induction of intestinal mucositis using 5-fluorouracil
• Assessment of mucin production in the duodenal segment
• Commiphora leptophloeos extract significantly protected the duodenal mucosa from damage
• Increased mucin production in treated mice compared to control
• Demonstrated potential for mitigating chemotherapy-induced gut toxicity