PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 17, 2026European Journal of Anaesthesiology0 citations

Prospective clinical evaluation of the Eleveld pharmacokinetic and pharmacodynamic model of propofol for moderate-to-deep sedation in adults

View Full Paper
MDMendy K. DriesensCBClemens R. M. BarendsDEDouglas J. Eleveld

Key Points

  • Evaluate the Eleveld pharmacokinetic and pharmacodynamic model's effectiveness for moderate-to-deep sedation (MDS).
  • Prospective clinical evaluation
  • Titration of propofol using the Eleveld model
  • Assessment of respiratory and hemodynamic stability
  • Achieved MDS with adequate respiratory parameters
  • Maintained hemodynamic stability during procedures
  • Facilitated safe completion of planned procedures

Abstract

The Eleveld propofol model can be used in TCI to achieve MDS while maintaining adequate respiratory and hemodynamic parameters, resulting in the safe completion of the planned procedures.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Driesens et al. (2026) studied this question.

synapsesocial.com/papers/69e1cf375cdc762e9d858226https://doi.org/10.1097/eja.0000000000002408
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Moderate-to-Deep Sedation Using Target-Controlled Infusions of Propofol and Remifentanil: Adverse Events and Risk Factors: A Retrospective Cohort Study of 2937 Procedures2019 · 48 citations
  2. 2European Society of Anaesthesiology and European Board of Anaesthesiology guidelines for procedural sedation and analgesia in adults2017 · 315 citations
  3. 3Pharmacokinetic–pharmacodynamic model for propofol for broad application in anaesthesia and sedation2018 · 307 citations
  4. 4Bispectral-Index-Guided Versus Clinically Guided Remifentanil/Propofol Analgesia/Sedation for Interventional Radiological Procedures: An Observer-Blinded Randomized Study2006 · 38 citations
  5. 5Bispectral Index Versus Standard Monitoring in Sedation for Endoscopic Procedures: A Systematic Review and Meta-Analysis2015 · 59 citations