Prospective clinical evaluation of the Eleveld pharmacokinetic and pharmacodynamic model of propofol for moderate-to-deep sedation in adults | Synapse
April 17, 2026
Prospective clinical evaluation of the Eleveld pharmacokinetic and pharmacodynamic model of propofol for moderate-to-deep sedation in adults
Key Points
Evaluate the Eleveld pharmacokinetic and pharmacodynamic model's effectiveness for moderate-to-deep sedation (MDS).
Prospective clinical evaluation
Titration of propofol using the Eleveld model
Assessment of respiratory and hemodynamic stability
Achieved MDS with adequate respiratory parameters
Maintained hemodynamic stability during procedures
Facilitated safe completion of planned procedures
Abstract
The Eleveld propofol model can be used in TCI to achieve MDS while maintaining adequate respiratory and hemodynamic parameters, resulting in the safe completion of the planned procedures.