Collapse of Immune Privilege in the Sweat Gland in a Sjögren Disease Patient With Generalized Anhidrosis

Key Points

• The aim is to investigate the collapse of immune privilege in the sweat glands of a patient with Sjögren disease and associated anhidrosis.
• Case study on a patient with Sjögren disease and generalized anhidrosis.
• Assessment of immune markers in sweat glands.
• Analysis of sweat gland function and morphology.
• Findings indicate a significant loss of immune privilege in sweat glands.
• Identification of inflammatory markers in the affected tissues.
• Generalized anhidrosis presents as a clinical manifestation of the autoimmune condition.