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October 16, 2023Journal of Experimental & Clinical Cancer Research78 citationsOpen Access

LncRNA FTO-IT1 promotes glycolysis and progression of hepatocellular carcinoma through modulating FTO-mediated N6-methyladenosine modification on GLUT1 and PKM2

FWFan WangYHYuhang HuHWHongda Wang

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Abstract

This study identified an important role of the FTO-IT1/FTO axis mediated m6A modification of glycolytic genes contributed to glycolysis and tumorigenesis of HCC, and FTO-IT1 might be served as a new therapeutic target for HCC.

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Wang et al. (2023) studied this question.

synapsesocial.com/papers/69e5d98262acec12c37f8a49https://doi.org/10.1186/s13046-023-02847-2
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