PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
October 16, 2023Journal of Experimental & Clinical Cancer Research80 citationsOpen Access

LncRNA FTO-IT1 promotes glycolysis and progression of hepatocellular carcinoma through modulating FTO-mediated N6-methyladenosine modification on GLUT1 and PKM2

FWFan WangYHYuhang HuHWHongda Wang

Key Points

Key points are not available for this paper at this time.

Abstract

This study identified an important role of the FTO-IT1/FTO axis mediated m6A modification of glycolytic genes contributed to glycolysis and tumorigenesis of HCC, and FTO-IT1 might be served as a new therapeutic target for HCC.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Wang et al. (2023) studied this question.

synapsesocial.com/papers/69e5d98262acec12c37f8a49https://doi.org/10.1186/s13046-023-02847-2
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation2009 · 16,419 citations
  2. 2NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif2009 · 105 citations
  3. 3LncRNA EPB41L4A-AS1 regulates glycolysis and glutaminolysis by mediating nucleolar translocation of HDAC22019 · 175 citations
  4. 4Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming2020 · 261 citations
  5. 5HDAC11 Regulates Glycolysis through the LKB1/AMPK Signaling Pathway to Maintain Hepatocellular Carcinoma Stemness2021 · 189 citations