S1PR3 expression independently predicts the cumulative incidence of relapse in adult B-cell acute lymphoblastic leukemia: a single-center retrospective analysis
Key Points
The research aims to determine if S1PR3 expression can independently predict relapse in adult B-cell acute lymphoblastic leukemia.
Retrospective analysis of S1PR3 expression in adult B-ALL patients
Assessment of cumulative incidence of relapse
Evaluation of risk stratification based on biomarker levels
Elevated S1PR3 expression correlates with higher relapse rates
S1PR3 serves as an independent predictor beyond traditional factors
Offers a potential target for new treatments.
Abstract
Elevated S1PR3 expression is an independent predictor of relapse in adult B-ALL, providing a novel biomarker to enhance risk stratification and guide potential targeted interventions.