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February 5, 2008Circulation392 citations

Prediction of the Localization of High-Risk Coronary Atherosclerotic Plaques on the Basis of Low Endothelial Shear Stress

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YCYiannis S. ChatzizisisMJMichael JonasACAhmet U. Coskun

Structured PICO

Does low endothelial shear stress predict the localization and development of high-risk coronary atherosclerotic plaques?

I
Intervention
Low Endothelial Shear Stress (ESS)
O
Outcome
Development of high-risk plaque and complexity/heterogeneity of atherosclerotic lesionssurrogate

Low endothelial shear stress is a predictor for the development of complex, high-risk coronary atherosclerotic plaques.

Abstract

The magnitude of low ESS determines the complexity and heterogeneity of atherosclerotic lesions and predicts the development of high-risk plaque.

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Chatzizisis et al. (2008) studied this question.

synapsesocial.com/papers/69e7e208a999fcd61821cc07https://doi.org/10.1161/circulationaha.107.695254
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