February 5, 2008Circulation
Prediction of the Localization of High-Risk Coronary Atherosclerotic Plaques on the Basis of Low Endothelial Shear Stress
Why the study?
Does low endothelial shear stress predict the localization and development of high-risk coronary atherosclerotic plaques?
Authors
Discussion
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Member takes
Implication
Low ESS may aid high-risk plaque detection on imaging; leaves open prospective validation for risk stratification or therapy.
Structured PICO
Does low endothelial shear stress predict the localization and development of high-risk coronary atherosclerotic plaques?
I
Intervention
Low Endothelial Shear Stress (ESS)
O
Outcome
Development of high-risk plaque and complexity/heterogeneity of atherosclerotic lesionssurrogate
Low endothelial shear stress is a predictor for the development of complex, high-risk coronary atherosclerotic plaques.
Cite This Study
Chatzizisis et al. (2008) studied this question.