Alterations in Primary Haemostasis in Patients With Liver Cirrhosis and Bacterial Infection

Key Points

• The aim is to investigate how liver cirrhosis and bacterial infection affect platelet aggregation and related factors.
• Examined platelet aggregation induced by ADP in patients with liver cirrhosis and infection.
• Assessed vWF:Ag, vWF:RCo, and FVIII levels in relation to infection severity.
• Analyzed associations with 30-day mortality.
• Impaired ADP-induced platelet aggregation correlates with infection severity.
• Elevated levels of vWF:Ag, vWF:RCo, and FVIII are noted in patients with platelet hyporesponsiveness.
• Higher levels of impairment are linked to increased 30-day mortality.