ABSTRACT Aim: This review seeks to obtain enough scientific evidence to provide knowledge regarding the effectiveness of using sodium hypochlorite (NaOCl) at various temperatures, i.e., warm, cold, and room temperature NaOCl, on posttreatment pain. Methods: Online databases were used to identify studies published till 2024, in which 551 studies were obtained during the initial search. After the screening, 7 studies were selected regarding the use of NaOCl at various temperatures, i.e., warm NaOCl, cold NaOCl, and room temperature NaOCl as endodontic irrigants, compared for the effect of posttreatment pain. Results: Upon reviewing 6 studies on the use of warm NaOCl as an irrigant, 4 studies (66.67%) showed an increase in posttreatment pain, whereas 3 out of 4 studies (75%) on using cold NaOCl showed a decrease in posttreatment pain. Conclusion: Overall, most of the studies that were included in this review suggested that using warm NaOCl increased posttreatment pain, using cold NaOCl reduced the posttreatment pain, whereas room temperature showed varied outcomes. Thus, according to the results, it can be concluded that using warm NaOCl as a root canal irrigant may increase posttreatment pain, whereas the use of cold NaOCl may decrease posttreatment pain.
Rao et al. (Mon,) studied this question.