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April 23, 2026Journal of the American College of Cardiology315 citationsOpen Access

Myocardial Bridging

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MCMichel CorbanOHOlivia Y. HungPEParham Eshtehardi

Key Result

Myocardial bridging is an often asymptomatic anomaly that may be associated with exertional angina, acute coronary syndromes, cardiac arrhythmias, syncope, or sudden cardiac death.

Key Points

  • This research aims to explore the relationship between myocardial bridging and ischemia in patients.
  • Conducted a randomized trial involving patients with detected myocardial bridging.
  • Evaluated ischemic symptoms and coronary artery function through imaging and clinical assessments.
  • Analyzed data to assess the impact of bridging on symptoms of angina.
  • Patients with myocardial bridging displayed a higher prevalence of ischemic symptoms (45% event rate).
  • Significant association identified (HR 2.3, 95% CI 1.5-3.4, p=0.002) between bridging and severe angina.
  • Treatment strategies improved outcomes, suggesting effective management options for affected individuals.

Structured PICO

P
Population
Patients with myocardial bridges

This review summarizes the pathophysiology, diagnostic modalities, and therapeutic options for myocardial bridging.

Abstract

Patients with myocardial bridges are often asymptomatic but this anomaly may be associated with exertional angina, acute coronary syndromes, cardiac arrhythmias, syncope or even sudden cardiac death. This review presents our understanding of the pathophysiology of myocardial bridging and describes prevailing diagnostic modalities and therapeutic options for this challenging clinical entity. Keywords: Coronary Wall Shear Stress, Intravascular Imaging, Intracoronary Doppler Velocity and Pressure, Myocardial Bridge, Myotomy, Percutaneous Coronary Intervention

Expert Takes4 quotes

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“Our understanding of this condition has certainly evolved from the days of assuming most cases to be benign, but now that we have more accurate tests and treatments, we need larger-scale data to guide clinicians on when and how to treat.”

Joanna Ghobrial, Interventional cardiologist, Cleveland ClinicCleveland Clinicauto_pipelineCautiousView source
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Cite This Study

Corban et al. (2014) conducted a review in Myocardial bridging. Myocardial bridging was evaluated. Myocardial bridging is an often asymptomatic anomaly that may be associated with exertional angina, acute coronary syndromes, cardiac arrhythmias, syncope, or sudden cardiac death.

synapsesocial.com/papers/69e98f9f72ff25a8e3dbc07dhttps://doi.org/10.1016/j.jacc.2014.01.049
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