The aim is to evaluate the effectiveness of exosomal miRNA in predicting patient responses to preoperative chemoradiotherapy in rectal cancer.
Utilized a signature panel of exosomal miRNA for assessment.
Explored the potential of a liquid biopsy assay for clinical use.
Demonstrated that specific miRNA profiles correlate with treatment response.
Indicated strong potential for clinical translation of findings.
Abstract
Our signature panel for predicting response to preoperative chemoradiotherapy has the potential for clinical translation as a liquid biopsy assay. (See Video Abstract).