What question did this study set out to answer?

To evaluate the efficacy and safety of computer-controlled local anesthetic delivery using 4% articaine with 1:200,000 epinephrine in elderly patients.

April 25, 2026Open Access

Efficacy of Computer-Controlled Local Anesthetic Delivery of 4 % Articaine With 1:200000 Epinephrine for Posterior Mandibular Anesthesia in Elderly Patients

Key Points

To evaluate the efficacy and safety of computer-controlled local anesthetic delivery using 4% articaine with 1:200,000 epinephrine in elderly patients.
Prospective comparative randomized controlled study conducted at Fivestarsdent LLC in Moscow.
Participants randomly assigned to receive anesthesia via either traditional cartridge syringe or computer-controlled syringe.
Assessment of efficacy and safety based on adverse reactions and complications post-anesthesia.
Computer-controlled delivery method showed significant advantages over traditional technique in reducing injection pain.
Data supported the efficacy and safety of using computer-controlled delivery in elderly patients, aligning with recent scientific literature.
The method is recommended as a preferred choice for local anesthesia in elderly patients.

Abstract

Background. The elderly population represents a distinct patient category with a high prevalence of dental and somatic diseases. Pharmacotherapy for comorbid conditions in elderly patients increases the risk of adverse effects and complications in dental practice. Stress and fear associated with pain and the injection procedure itself can provoke tachycardia, elevated blood pressure, and lead to refusal of necessary treatment. Recent scientific reviews and statistics demonstrate a significant reduction in injection pain with computer-controlled delivery of local anesthetic compared to the traditional technique. However, the number of studies on the application of this technology in elderly and senile patients, with comprehensive assessment of hemodynamic parameters, stress levels, and anesthesia efficacy and safety, remains limited. Objective. To evaluate the efficacy and safety of a 4 % articaine-containing local anesthetic with a 1:200,000 vasoconstrictor administered via computer-controlled delivery for the treatment of dental diseases in the retromolar area in elderly patients. Materials and Methods. A prospective comparative randomized controlled study was conducted at the dental clinic of Fivestarsdent LLC (Moscow). Patients were randomly allocated into two groups: the first group received anesthesia using a traditional cartridge syringe, the second group using a “Injecta” computer-controlled syringe. The efficacy and safety of anesthesia were assessed based on adverse reactions and complications following mandibular anesthesia with "Articaine INIBSA." Results. The obtained results demonstrate significant advantages of the computer-controlled method for local anesthetic delivery in elderly patients compared to the traditional technique and are consistent with contemporary scientific literature data. Conclusion. The computer-controlled delivery method of 4 % articaine local anesthetic 1:200000 using computer-assisted anesthetic delivery system “Injecta” can be recommended as the method of choice for local anesthesia in elderly and senile patients during dental treatment.

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