What question did this study set out to answer?

The study aimed to evaluate the relationship between neonatal cerebrovascular stability index and oxygenation with neurodevelopmental outcomes at three months in congenital heart disease.

April 26, 2026JACC Advances0 citationsOpen Access

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Neonatal Cerebrovascular Stability Index and Oxygenation With 3-Month Neurodevelopmental Outcomes

AIAshley Ibrahim JVJodie K. Votava-SmithChildren's Hospital of Los Angeles JWJohn C. WoodChildren's Hospital of Los Angeles

Key Points

The study aimed to evaluate the relationship between neonatal cerebrovascular stability index and oxygenation with neurodevelopmental outcomes at three months in congenital heart disease.
Evaluated associations between cerebrovascular stability index (CSI) and regional oxygenation (rcSO2) with 3-month outcomes.
Examined cognitive and motor outcomes in congenital heart disease (CHD) subgroups.
Identified differences in associations among the groups.
CSI and rcSO2 were associated with cognitive and motor outcomes at 3 months, indicating a link between cerebrovascular health and development.
Differential associations indicated variability in outcomes among CHD subgroups.

Abstract

Neonatal CSI and rcSO2 associated with 3-month cognitive and motor outcomes in CHD and CHD subgroups, and groups differed in their directional associations. Future studies should explore CSI as an indicator of risk for developmental delays in CHD.

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Neonatal Cerebrovascular Stability Index and Oxygenation With 3-Month Neurodevelopmental Outcomes

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Abstract

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